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. 2016 Mar 9;11(5):1587–1594. doi: 10.3892/etm.2016.3134

Figure 5.

Figure 5.

Alterations in the migratory abilities of the human ovarian carcinoma cells with directional high lymphatic metastasis (SKOV3-PM4) and the human lymphatic endothelial cells (HLECs; hematoxylin-eosin staining; magnification, ×400) ability. SKOV4-PM4s were cultured in (A) normal medium and (B) the supernatant of the HLECs. The migratory ability of the SKOV4-PM4s cultured in the supernatant of the HLECs were markedly increased, as compared with the SKOV4-PM4s cultured in normal medium. HLECs were cultured in (C) normal medium and (D) the supernatant of the SKOV3-PM4s. The invasion abilities of the HLECs cultured in the supernatant of the SKOV4-PM4s were markedly increased, as compared with the HLECs cultured in the normal medium.