Table III.
Multivariate analyses of prognostic factors for overall survival in 279 patients undergoing TACE for hepatocellular carcinoma.
| Multivariate analysis | |||
|---|---|---|---|
| Variables | Value | Hazard ratio (95% CI) | P-value |
| NLRa | |||
| Mean ALT, µ/1 (range) | 56.6 (8–304) | 1.472 (1.099–1.971) | 0.010 |
| Mean AFP, ng/ml (range) | 751.2 (1.26–1,210,000) | 1.677 (1.259–2.233) | <0.001 |
| NLR, n | |||
| ≤2.6 | 139 | 1.382 (1.037–1.842) | 0.027 |
| >2.6 | 140 | ||
| dNLRa | |||
| Mean ALT, µ/1 (range) | 56.6 (8–304) | 1.469 (1.098–1.966) | 0.010 |
| Mean AFP, ng/ml (range) | 751.2 (1.26–1,210,000) | 1.720 (1.294–2.287) | <0.001 |
| dNLR, n | |||
| ≤1.8 | 153 | 1.445 (1.086–1.923) | 0.012 |
| >1.8 | 126 | ||
a
NLR and dNLR were used as covariates, adjusted by ALT and AFP. ALT, alanine aminotransferase; ALP, alkaline phosphatase; NLR, neutrophil to lymphocyte ratio; dNLR, derived NLR.