Table II.
Comparison of FBG, AUCglu, IGF-1 and IGFBP-3 levels between the two groups (the means ± SD).
| Group | Treatment | Time | FBG (mmol/l) | AUCglu | IGF-1 (ng/ml) | IGFBP-3 (µg/ml) |
|---|---|---|---|---|---|---|
| High-dose group | Before treatment | 4.50±1.84 | 621.25±34.62 | 259.42±126.31 | 4.06±7.22 | |
| After treatment | 1 month | 4.61±1.26 | 652.15±29.84 | 295.72±90.43a | 4.03±1.01 | |
| 3 months | 4.81±3.91a,b | 690.14±102.52 | 297.33±106.35a | 4.96±5.66a,b | ||
| 6 months | 5.03±2.95a,b | 721.25±36.95 | 298.15±96.54a | 5.01±4.15a,b | ||
| Low-dose group | Before treatment | 4.52±1.84 | 629.87±64.59 | 249.58±116.68 | 4.10±0.85 | |
| After treatment | 1 month | 4.59±2.12 | 666.55±47.95 | 271.51±146.51a | 4.09±1.62 | |
| 3 months | 4.72±1.95a,b | 671.15±68.45 | 281.19±95.41a,d | 4.89±3.19a,b | ||
| 6 months | 4.77±1.11a,b,d | 703.21±85.21 | 290.68±81.6a,b | 4.93±0.95a,b |
Comparison before treatment
a
P<0.05; comparison after 1 month after treatment
b
P<0.05; comparison after 3 months after treatment
c
P<0.05; comparison after 6 months of treatment with high-dose group
d
P<0.05. FBG, fasting blood glucose; AUCglu, area under blood glucose curve; IGF-1, insulin-like growth factor-1; IGFBP-3, insulin-like growth factor binding protein-3.