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Inhibition of OGT using RNAi-OGT decreased the cellular migratory ability of ECA-109 cells. Transwell migration assays were performed using Eca-109 cells transfected with (A) RNA-Control or (B) RNAi-OGTB for 72 h. (C) The number of cells penetrating the matrix for the control and RNAi-OGT groups, revealing a significant reduction in the RNAi-OGT group (*P=0.024 vs. cells infected with negative control shRNA). RNAi, RNA interference; OGT, O-linked N-acetylglucosamine transferase.
