Table I.

Regulatory associations between miRNAs and PTEN.

Gene association	Differentially-expressed network	Related network	Global network
PTEN
miRNAs targeting the gene	miR-106b, miR-17, miR-19a, miR-20a, miR-21, miR-221, miR-26a, miR-494	miR-106b, miR-17, miR-19a, miR-20a, miR-21, miR-214, miR-221, miR-222, miR-26a, miR-29a, miR-494, miR-216a	miR-106b, miR-141, miR-17, miR-17–5p miR-18a miR-19a, miR-19b, miR-20a, miR-21, miR-214, miR-21–5p, miR-217, miR-22, miR-221, miR-221–3p, miR-222, miR-222–3p, miR-26a, miR-29a, miR-29b-3p, miR-494, miR-519a-3p, miR-519d, miR-93–5p
miRNAs regulated by the gene	miR-19a, miR-21, miR-25	miR-19a, miR-21, miR-25	miR-19a, miR-21, miR-22, miR-25, miR-302, miR-302a, miR-302b, miR-302c, miR-302d, miR-302f

miR/miRNA, microRNA.