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Effect of TPX2 on the proliferation of the renal cell carcinoma (RCC) cells. The expression vector for TPX2 or siRNA oligonucleotide were transfected into the four RCC cell lines. (A) Transfection was evaluated by western blotting; (B) proliferative ability of the RCC cells was analyzed by WST-1 assay; and (C) tumor growth was evaluated in an animal xenograft model. Cont, control; si, small interfering; TPX2, targeting protein for Xenopus kinesin-like protein 2; wk/s, week/s.
