Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Western blot analysis demonstrating that TPX2 increased the activity of the Akt/mTOR pathway in renal cell carcinoma (RCC) cells. In the ACHN and NC65 cell lines, although TPX2 did not affect the protein expression of Akt and mTOR/p70S6K, high expression of TPX2 increased the phosphorylation of the components in the Akt/mTOR pathway. TPX2, targeting protein for Xenopus kinesin-like protein 2; si, small interfering; p-, phosphorylated; mTOR, mammalian target of rapamycin.
