Figure 8.

Summary of the main findings of the study. The relative size of arrows is proportional to the number of sub-pathways being significantly upregulated or downregulated within each pathway compared to controls. Color coding is congruent with the pathway analysis, i.e. red for upregulated and blue for downregulated pathways. When a candidate gene was associated and suggested to play a main role in the signaling pathway, its name is noted in parenthesis. STD, standard diet; HFD, high-fat diet; pWAT, perigonadal white adipose tissue. This figure will be best described with colors at the online version.