Table 2. Maternal markers affecting different birth outcomes as determined by regression model analyses.
Infant birth weight (IBW) distribution |
Infant birth weight for gestational age (IBW-GA) distribution |
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Birth outcome | Maternal factors a | Maternal factors b | Maternal factors a | Maternal factors b |
IBW | ICAM-1 (p = 0.012)VEGF (p = 0.002)ET-3 (p = 0.087)VCAM-1 (p = 0.074) | VEGF (p < 0.01)ET-3 (p < 0.01)VCAM-1 (p < 0.05) | VCAM-1 (p = 0.007)VEGF (p = 0.067)ICAM-1 (p = 0.078)BMI (p = 0.094)DiaBP (p = 0.090)ET-1 (p = 0.179) | BET-1 (p = 0.03)ET-2 (p = 0.05)MMP-9 (p = 0.02)VEGF (p = 0.003) |
GA | MMP-2 (p = 0.010)VEGF (p = 0.037)ET-1 (p = 0.107)ICAM-1 (p = 0.076) | MMP-2 (p < 0.06)VEGF (p = 0.01)ET-1 (p = 0.01) | – | – |
IBW/GA | BET-1 (p = 0.032)MMP-2 (p = 0.033)MMP-9 (p = 0.021)VEGF (p < 0.001)BMI (p = 0.106) | BET-1 (p < 0.01)MMP-2 (p < 0.05)VEGF (p < 0.01)BMI (p < 0.01) | – | – |
<25th percentile IBW | BET-1 (p = 0.021),ET-2 (p = 0.014),ISOP (p = 0.074),VCAM-1(p = 0.077),MMP-9 (p = 0.003) | BET-1 (p = 0.01)ET-2 (p = 0.02)MMP-9 (p = 0.01) | SysBP (p = 0.035)DiaBP (p = 0.046)BET-1 (p = 0.065)ET-2 (p = 0.084)MMP-7 (p = 0.067)MMP-9 (p = 0.036) | BET-1 (p = 0.01)ET-2 (p = 0.02)MMP-9 (p = 0.01) |
>75th percentile IBW | ET-3 (p = 0.097),VEGF (p < 0.001) | VEGF (p = 0.002) | VCAM-1 (p = 0.008)VEGF (p = 0.078) | VEGF (p = 0.002) |
Best subsets regression results (e.g. <25th percentile, r = 0.46; >75th percentile, r = 0.36).
Polytomous logistic regression results.