Figure 1.

Dose-dependent proliferation inhibition rates of nitroxoline on various cell types, as determined by methyl thiazolyl tetrazolium assay. Different cell lines exhibit differential sensitivities to nitroxoline treatment in vitro. Dose-response curves were obtained using a logistic nonlinear regression analysis model. Data are presented as mean ± standard deviation from quadruplicate samples of at least two independent experiments. HUVEC, human umbilical vein endothelial cells; HELF, human embryonic lung fibroblast.