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. 2015 Oct 30;4:36. Originally published 2015 Feb 4. [Version 2] doi: 10.12688/f1000research.6077.2

PMC4841201.1; 2015 Feb 4
PMC4841201.2; 2015 Oct 30

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Copyright: © 2015 Siranosian B et al.

This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — a) Density plot of TUD values for the 4-mer GATC. Individual subclusters form well-defined groups. B3 phages have GATC usage four times what is expected, much higher than other B subclusters. b) Repeat of (a) with the 6-mer GGATCC. B3 phages use this 6-mer greater than four times what is expected. c) GATC usage deviation in a sliding window (5kb, 1kb step size). Each line represents the mean value in the specified subcluster. The increase in GATC usage is genome-wide, indicative of a global change in usage frequency. d) Repeat of (c) with the 6-mer GGATCC. Increased usage is also genome-wide.