Supplementary Figure 1. Hierarchical clustering of all 663 phage genomes.

Hierarchical clustering dendrogram constructed on pairwise Euclidean distances between all 663 phages in the mycobacteriophage database. In almost every case, phages are placed in a monophyletic clade with members of their subcluster, highlighting the concordance between alignment-based and alignment-free methods for comparison for these genomes. Some clusters (F, C, D, M and L) form monophyletic clades, while others (B, for example) are grouped in different parts of the dendrogram. A larger version of this figure can be downloaded from .