Table 2. Summary of statistical analysis of active and inactive classes of influenza A and B neuraminidase inhibitors.

Descriptor	Influenza A			Influenza B
	Active	Inactive	p-value	Active	Inactive	p-value
MW	343.234 ± 56.916	328.415 ± 83.823	0.085	312.466 ± 44.641	357.692 ± 76.866	<0.05
RBN	7.061 ± 2.183	5.248 ± 2.681	<0.05	5.689 ± 2.043	7.233 ± 2.561	<0.05
nCIC	1.514 ± 0.655	2.109 ± 1.316	<0.05	1.444 ± 0.546	1.709 ± 0.852	<0.05
nHDon	4.743 ± 1.257	4.321 ± 2.029	<0.05	4.578 ± 1.34	4.849 ± 1.561	0.302
nHAcc	7.777 ± 1.502	7.204 ± 2.153	<0.05	7.156 ± 1.731	8.337 ± 1.334	<0.05
ALogP	0.049 ± 1.256	0.853 ± 2.475	<0.05	−0.128 ± 1.291	−0.017 ± 1.602	0.67
TPSA	125.205 ± 24.37	120.033 ± 37.06	0.169	114.592 ± 27.661	134.168 ± 25.007	<0.05
Qm	0.163 ± 0.02	0.179 ± 0.055	<0.05	0.158 ± 0.013	0.168 ± 0.018	<0.05
Energy	−0.274 ± 0.083	−0.246 ± 0.119	<0.05	−0.276 ± 0.099	−0.249 ± 0.089	0.129
Dipole moment	4.101 ± 1.972	4.328 ± 2.003	0.336	3.831 ± 1.601	4.364 ± 2.011	0.101
HOMO	−0.352 ± 0.011	−0.343 ± 0.015	<0.05	−0.351 ± 0.009	−0.35 ± 0.013	0.573
LUMO	−0.006 ± 0.018	−0.021 ± 0.022	<0.05	−0.013 ± 0.01	−0.003 ± 0.023	<0.05
HOMO-LUMO	0.346 ± 0.023	0.322 ± 0.03	<0.05	0.339 ± 0.014	0.347 ± 0.029	<0.05