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. Author manuscript; available in PMC: 2017 Apr 13.
Published in final edited form as: Cell Host Microbe. 2016 Apr 13;19(4):529–540. doi: 10.1016/j.chom.2016.03.005

Figure 4.

Figure 4

Characterization of markers of SIV susceptibility. A-G, Vaginal lymphocytes from uninfected, acutely and chronically SIVmac251-infected RMs were stained by CD3, CD4, CD8, CCR5, CCR6 and Ki-67. B-G, All cells analyzed were gated on the live CD4+CD8-CD3+ cell populations. Bars indicate the mean. H, Vaginal tissue from animal EB11 was stained for SIV antigens Gag (Green) and Env (Red), and Ki-67 (Red or Blue in inset) to measure whether SIV infected cells were actively dividing. Scale bars measure 10µm unless indicated. I-J, The frequency and MFI of CCR6+ cells was measured on the CD4 T cell population after 5 days of infection. PBMC from uninfected RMs were cultured with or without SIVmac251. Box plots indicate the median and interquartile range. * p < 0.05.