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. 2016 Apr 11;11:1305–1321. doi: 10.2147/IJN.S92257

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© 2016 Liao et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited.

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(A) Activation of caspases-3, -8, and -9 in MCF-7 cells incubated with WP1-SeNPs for 24 hours. (B) Western blot analysis for the expression of FADD. β-actin was used to adjust for differences in loading. (C) The possible signaling pathway of WP1-SeNPs induced apoptosis in MCF-7 cells.

Notes: ^a–dRepresents a significant difference among data in different groups at P<0.05 level.

Abbreviations: WP1-SeNPs, walnut peptide 1-selenium nanoparticles; FADD, Fas-associated death domain protein; ROS, reactive oxygen species.