TABLE 1.
LC+ | LC+Cereb | Peri LC | LC Miss | cNTS+ | cNTS Miss | |
---|---|---|---|---|---|---|
I) DIENCEPHALON | ||||||
Hypothalamus | ||||||
Dorsomedial Hypothalamus | 2 | 2 | 2 | 0 | 2 | 0 |
Lateral Hypothalamus | 2 | 2 | 1 | 1 | 2 | 0 |
Perifornical Area | 0 | 1 | 0 | 0 | 0 | 0 |
Posterior Hypothalamus | 1 | 1 | 2 | 0 | 1 | 0 |
II) MESENCEPHALON | ||||||
Periaqueductal Gray | 3 | 2 | 2 | 0 | 2 | 1 |
III) PONS | ||||||
Dorsal Raphé | 2 | 1 | 1 | 0 | 1 | 0 |
LC contralateral or LC | 3 | 2 | 2 | 0 | 2 | 1 |
Subcoeruleus | 3 | 3 | 1 | 0 | 3 | 0 |
Parabrachial Nuclei | 3 | 2 | 3 | 0 | 0 | 0 |
Kölliker-Fuse | 3 | 2 | 2 | 0 | 2 | 0 |
A5 | 2 | 3 | 2 | 0 | 3 | 0 |
Paragigantocellular nucleus | 2 | 0 | 1 | 0 | 1 | 1 |
IV) MEDULLA | ||||||
Amb/RVL/CVL | 2 | 2 | 2 | 0 | 2 | 1 |
Area Postrema | 1 | 1 | 1 | 0 | ND | ND |
Pre-Bötz/Bötz | 2 | 1 | 1 | 0 | 2 | 0 |
Caudal NTS | 3 | 3 | 3 | 0 | ND | ND |
Facial | 2 | 1 | 2 | 0 | 1 | 0 |
Intermediate NTS | 2 | 1 | 2 | 0 | 3 | 1 |
Inferior Olive | 3 | 2 | 1 | 1 | 1 | 0 |
LRtPC/LRt | 3 | 3 | 1 | 0 | 2 | 0 |
Medullary Raphé | 3 | 3 | 3 | 0 | 1 | 0 |
Pyramidal Tract | 3 | 2 | 2 | 0 | 1 | 2 |
Retrotrapezoid Nucleus | 3 | 3 | 2 | 1 | 2 | 0 |
Spinal Trigeminal Tract | 2 | 2 | 2 | 2 | 2 | 2 |
SpVe/Mve | 1 | 2 | 1 | 0 | 1 | 0 |
Scoring: “0”: 0–1 neuron identified; “1”: 2–5 neurons identified. The numbers in black represents a weak labelling pattern. “2”: 6–10 neurons identified. The numbers in green represents a median labelling pattern. “3”: >10 neurons identified. The numbers in red represents a strong labelling pattern. Highlighted areas in yellow represent regions involved in ventilatory control. N=3; ND: not determined.