Table 1. Cardiovascular disease risk factors among people with and without new onset depression at baseline.
| No depression at baseline (n/N = 1,316,831/1,356,578)† | New onset depression at baseline (n/N = 39,747/1,356,578) | History of depression (n/N = 367,117/1,937,360) | ||||
|---|---|---|---|---|---|---|
| n | (%) | n | (%) | n | (%) | |
| Women | 604,278 | (45.9) | 25,381 | (63.9) | 245,989 | (67.0) |
| Mean age, years (SD) | 47.3 | (15.1) | 47 | (15.0) | 48.3 | (15.6) |
| Ethnicity* | ||||||
| White | 587,711 | (90.4) | 23,153 | (92.8) | 219,042 | (59.7) |
| South Asian | 19,151 | (2.9) | 593 | (2.4) | 4,077 | (1.1) |
| Black | 21,150 | (3.3) | 615 | (2.5) | 3,673 | (1.0) |
| Socioeconomic status | ||||||
| Least deprived | 278,418 | (21.1) | 7,016 | (17.7) | 62,384 | (17.0) |
| Most deprived | 242,922 | (18.4) | 9,115 | (22.9) | 88,687 | (24.2) |
| Smoking* | ||||||
| Non smoker | 45,142 | (21.9) | 1,853 | (18.2) | 11,706 | (3.2) |
| Ex smoker | 72,002 | (34.9) | 3,142 | (30.8) | 26,883 | (7.3) |
| Current smoker | 88,925 | (43.2) | 5,193 | (51.0) | 43,285 | (11.8) |
| Diabetes mellitus | 33,390 | (2.5) | 1,386 | (3.5) | 14,197 | (3.9) |
| Mean body mass index, kg/m2 (SD) | 26.3 | (5.0) | 26.5 | (5.5) | 27.0 | (5.9) |
| Mean blood pressure*, mmHg (SD) | ||||||
| Systolic | 130.6 | (19.1) | 128.4 | (18.8) | 129.0 | (19.0) |
| Diastolic | 78.7 | (10.2) | 77.8 | (10.2) | 78.0 | (10.4) |
| Mean lipid concentration*, mg/dL (SD) | ||||||
| Total cholesterol | 5.4 | (1.1) | 5.4 | (1.2) | 5.0 | (1.2) |
| High density lipoprotein | 1.4 | (0.4) | 1.4 | (0.4) | 1.0 | (0.4) |
| Medication use | ||||||
| Statins | 30,217 | (2.3) | 1,275 | (3.2) | 15,682 | (4.3) |
| Any blood pressure-lowering drug | 178,605 | (13.6) | 7,671 | (19.3) | - | - |
| Mean number of consultations in last year (SD) | 3.8 | (5.0) | 10.0 | (8.3) | 8.0 | (8.3) |
Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; HDL, high density lipoprotein; SD; standard deviation; SBP, systolic blood pressure
† This category refers to the reference group from cohort of new onset depression at baseline (total n = 1,356,578): n = 39,747 with depression versus n = 1,316,831 with no depression at baseline.
* Missing values in the whole sample (1,937,360) for ethnicity = 50.25%; smoking = 84.0%; systolic blood pressure = 60.2%; diastolic blood pressure = 60.2%; total cholesterol = 90.0% and high density lipoprotein = 95.0%.; Missing values in the study population (1,356,578) for ethnicity = 36.89%; smoking = 77.7%; systolic blood pressure = 50.0%; diastolic blood pressure = 50.0%; total cholesterol = 89.0% and high density lipoprotein = 92.7%.