Table 2. Cumulative incidence rate (IR) of 12 cardiovascular diseases per 100,000 person-years at risk (PYR) among people with new onset depression at baseline and with history of depression prior to baseline.
| No depression at baseline (n/N = 1,316,831/1,356,578)† | History of depression (n/N = 367,117/1,937,360) | New onset depression at baseline (n/N = 39,747/1,356,578) | ||||
|---|---|---|---|---|---|---|
| N events | IR/100,000 PYR | N events | IR/100,000 PYR | N events | IR/100,000 PYR | |
| Coronary | ||||||
| Stable angina | 7,983 | 87 | 3,106 | 147 | 279 | 108 |
| Unstable angina | 3,439 | 38 | 1,536 | 73 | 137 | 53 |
| Myocardial infarction | 11,085 | 121 | 3,257 | 154 | 285 | 110 |
| Unheralded coronary death | 3,981 | 44 | 1,124 | 53 | 122 | 47 |
| Other myocardial | ||||||
| Heart failure | 9,132 | 100 | 3,026 | 143 | 265 | 102 |
| Cardiac arrest/sudden cardiac death | 2,403 | 26 | 622 | 30 | 70 | 27 |
| Cerebrovascular | ||||||
| Transient ischaemic attack | 7,538 | 82 | 2,643 | 125 | 247 | 95 |
| Ischaemic stroke | 4,168 | 46 | 1,312 | 62 | 119 | 46 |
| Subarachnoid haemorrhage | 819 | 9 | 315 | 15 | 34 | 13 |
| Intracerebral haemorrhage | 1,610 | 18 | 533 | 25 | 45 | 17 |
| Abdominal and lower limb | ||||||
| Peripheral arterial disease | 7,423 | 81 | 2,661 | 126 | 261 | 101 |
| Abdominal aortic aneurysm | 2,261 | 25 | 550 | 26 | 55 | 21 |
| Total CVD | 74,821 | 819 | 25,247 | 1,198 | 2,322 | 898 |
† This category refers to the reference group from cohort 1 -new onset depression at baseline (total n = 1,356,578): n = 39,747 with depression versus n = 1,316,831 with no depression at baseline.