Table 4. Decreased resting state functional connectivity in nonHAND group compared to seronegative control.
Seed | Connected regions | Side | MNI coordinates | Maximum t | Mean r value | P value | |||
---|---|---|---|---|---|---|---|---|---|
x | y | z | nonHAND | seronegative control | |||||
Left Precuneus | Superior Medial Frontal | R | 3 | 63 | 30 | 5.27 | -0.102 | 0.033 | <0.001 |
Angular | R | 57 | -57 | 36 | 4.81 | -0.068 | 0.091 | <0.001 | |
Hippocampus | R | 27 | -18 | -15 | 4.48 | -0.193 | 0.024 | <0.001 | |
Middle Orbitofrontal | L | -6 | 63 | -9 | 4.24 | 0.043 | 0.117 | <0.001 | |
Precuneus | R | 15 | -60 | 30 | 4.07 | 0.428 | 0.485 | <0.001 | |
Middle Temporal | R | 63 | -15 | -15 | 3.84 | -0.171 | 0.004 | <0.001 | |
Superior Orbitofrontal | R | 24 | 63 | 0 | 3.67 | -0.065 | 0.019 | <0.005 | |
Cerebellum | L | -48 | -57 | -39 | 3.53 | -0.028 | -0.036 | <0.001 | |
Right Precuneus | Hippocampus | R | 27 | -18 | -18 | 4.14 | -0.157 | 0.054 | <0.001 |
Precuneus | R | 6 | -48 | 12 | 4.08 | 0.398 | 0.492 | <0.001 | |
Angular | R | 57 | -57 | 36 | 3.91 | -0.001 | 0.063 | <0.001 | |
Middle Temporal | R | 69 | -12 | -9 | 3.78 | -0.198 | -0.042 | <0.001 | |
Middle Temporal | L | -51 | -21 | -12 | 3.76 | -0.174 | -0.134 | <0.001 | |
Precuneus | R | 12 | -60 | 27 | 3.49 | 0.547 | 0.591 | <0.005 | |
Middle Orbitofrontal | R | 6 | 60 | -6 | 3.46 | -0.014 | 0.089 | <0.005 |