Skip to main content
. 2016 Apr 22;11(4):e0153806. doi: 10.1371/journal.pone.0153806

Fig 4. Alteration of lysyl oxidase (LOX) expression diabetic skin.

Fig 4

(A) LOX family members mRNA expression in diabetic and non-diabetic control skin. Lox family mRNA levels were normalized to the housekeeping gene 36B4, as an internal control for quantification. Data are relative levels to 36B4. Mean±SEM. N = 6. (B) LOX protein levels were determined by Western analysis and normalized by β-actin (loading control). Insets (left panel) show representative Western blots. Data are expressed as mean±SEM, N = 6, *p<0.05. (C) Collagen solubility by pepsin digestion was determined by HPLC (see Methods for details). Mean±SEM. N = 12, *p<0.05.