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. 2016 Apr 22;11(4):e0154053. doi: 10.1371/journal.pone.0154053

Fig 2. Nanocarrier-mediated cell-cell binding in vitro.

Fig 2

A. Schematic illustration of the design of nanocarriers with a representative image of the desired biological readout. “Mono-arm” (Ac-G5-dendrimer-sE-sel, Left) and “double-arm” (Ac-G5-dendrimer-sE-sel/VEGF, Right) for EPC coating. B. In vitro EPC-EC binding assay. “Mono-arm” and “double-arm” nanocarrier-decorated DsRad+ EPC displayed an increased binding capability to EC monolayer. E-selectin blocking antibody inhibited nanocarrier-mediated association of EPC-EC. Quantitative data of DsRed signals. Data are presented as mean ± SD of three independent assays in which samples were duplicated. Insert: Representative images of DsRed fluorescence in wells.