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. 2016 Apr 22;11(4):e0154053. doi: 10.1371/journal.pone.0154053

Fig 6. Targeted systemic delivery of nanocarrier-coated MSC to wound tissues.

Fig 6

A. In vivo IVIS imaging shows an increased Ac-G5-dendrimer-sE-sel nanocarrier-coated Luc2+-MSC homed to wound tissues compared to either uncoated Luc2+-MSC or Ac-G5-BSA-coated Luc2+-MSC at various time points. B. Quantitative data of bioluminescence signals in each group (n = 4/group) at various time points. C. Bioluminescence imaging shows Ac-G5-dendrimer-sE-sel nanocarrier-coated Luc2+-MSC selectively homed to skin wound tissues but not other organs, as demonstrated by IVIS scanning of the harvested lung, heart, liver, spleen, kidney, femur, normal and wounded skins on Day 8.