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. 2016 Apr 22;11(4):e0154025. doi: 10.1371/journal.pone.0154025

Table 2. Medical therapy.

All, n = 8,342 Quartile 1, n = 2,046 Quartile 2, n = 1,899 Quartile 3, n = 2,090 Quartile 4, n = 2,307 p
ACE inhibitor, n (%) 3223 (52) 733 (53) 889 (50) 828 (49) 773 (52) <0.0001 *
ARB, n (%) 1504 (24) 298 (21) 426 (24) 407 (25) 373 (26) 0.016
Aldosteron-antagonist, n (%) 577 (9) 101 (7) 122 (7) 139 (9) 215 (15) <0.0001 §#
Beta-blocker, n (%) 4166 (67) 954 (76) 1194 (64) 1086 (65) 932 (63) <0.0001 *
Statin, n (%) 4706 (71) 1080 (66) 1420 (76) 1207 (72) 999 (68) <0.0001 *§#
Aspirin, n (%) 7001 (98) 1813 (99) 1323 (98) 1712 (97) 1553 (98) 0.004 §
P2Y12 inhibitor, n (%) 7010 (98) 1800 (98) 1922 (98) 1729 (98) 1559 (98) 0.926
Dual antiplatelet therapy, n (%) 6866 (96) 1800 (98) 1868 (95) 1679 (95) 1519 (95) <0.0001 *
Calcium-channal blocker, n (%) 1637 (26) 291 (19) 489 (27) 438 (27) 419 (29) <0.0001 *
Nitrates, n (%) 1326 (22) 191 (13) 351 (20) 381 (25) 403 (29) <0.0001 *§#

Significant differences according to quartiles:

* = Q1 vs. Q2,

= Q1 vs. Q3,

= Q1 vs. Q4,

§ = Q2 vs. Q3,

= Q2 vs. Q4,

# = Q3 vs. Q4.

Quartile 1 = <58 years;

Quartile 2 = 58–65 years;

Quartile 3 = 66–73 years;

Quartile 4 = >73 years.

Abbreviations:

ACE = angiotensin-converting-enzyme;

ARB = angiotensin receptor blocker;

p = p-value.