Table 1. Location of the NF-κB-binding motif AGGTGT within the promoter sequences of various prostate-enriched genes.
Promoter | Position(s) |
---|---|
PAcP | −1254 |
PSA | −3984 |
Nkx-3.1 | −1407 |
MIC-1 | −2261 |
−3991 | |
DD3a | −3642 |
−3585 | |
−2791 | |
−1895 |
aComputer analyses of the promoter sequence of the DD3 gene revealed the presence of NF-κB-binding motifs with AGGTGG sequence that exhibit a similar binding activity to AGGTGT (Figure 8C, lane 1 versus lane 7).