Table 3.

Section 3: Associations between neuropathological findings and all-cause dementia considering all data from the autopsy subset of the original cohort (left columns) and considering only the subset of those data collected at research clinic study visits (right columns), along with bootstrapping results (far right column)^*

	All data			Clinic-only data			Bootstrap results
Finding	RR	CI	p value	RR	CI	p value	p value
CERAD	1.73	1.35, 2.21	<0.0001	1.63	0.88, 3.02	0.12	0.70
Braak	2.27	1.84, 2.79	<0.0001	3.43	1.90, 6.19	<0.0001	0.006
Hippocampal sclerosis	1.47	1.11, 1.95	0.008	2.28	1.43, 3.66	0.0006	0.034
Amyloid angiopathy	1.42	1.16, 1.74	0.001	1.69	1.05, 2.73	0.030	0.22
Neocortical Lewy bodies	1.45	1.04, 2.03	0.029	1.83	1.03, 3.27	0.040	0.33
Cerebral cortical microinfarct	1.42	1.15, 1.74	0.001	2.00	1.23, 3.25	0.005	0.018
Deep cerebral microinfarct	1.44	1.17, 1.76	0.0006	1.59	0.99, 2.57	0.06	0.48
Cystic infarct	1.55	1.26, 1.89	<0.0001	2.35	1.54, 3.58	0.0001	0.004

^*Bootstrapping p values were obtained using analogous procedures to those described in the note to Table 2, except we used Poisson regression to obtain relative risks.