Table 1.

Parameters in the discussed myocardial G&R models

		Models	No. of parameters	BR	GM	LM	Remarks
Cellular-based	Hypertrophy	Rydall et al.33	>= 100	All	X	X	Note: Although all parameters listed here are biochemical reaction rates, it is unclear as to where the transition from biochemical to growth rates are in the model.
	ECM remodeling	Jin et al.39	15	3	9	3
Continuum-based	Hypertrophy	Lin and Taber53	9	X	9	X	Focused on developmental G&R
		Goktepe et al.73	8	X	2	6	Assumed a different set of parameters for stress and strain-mediated G&R constitutive laws
		Lee et al.60	8	X	2	6	Assumed a different set of parameters for atrophy and hypertrophy
		Kerckhoff et al.62	15	X	6	4
	ECM remodeling	Wilson et al.91	11	X	2	9	Parameters are associated with constituents in the arteries (collagen, elastin and smooth muscle). Only parameters associated with G&R are considered –parameters associated with the mechanical properties are listed here.

Abbreviations: BR, biochemical reaction rates; GM, growth/mass production rates; LM, limits/threshold/homeostatic states associated with G&R: ECM, extracellular matrix.