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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Exp Eye Res. 2015 Oct 22;145:173–186. doi: 10.1016/j.exer.2015.10.014

Figure 2. Animal-specific, EG (dotted line) versus Control Eye (solid line) comparisons of Anterior Scleral Canal Opening (ASCO - blue) and Optic Nerve – ASCO (ON-ASCO - green) and the ASCO-to- Optic Nerve ASCO Gap Distance (ASCO-ON-ASCO) (green arrow upper left).

Figure 2

ASCO fitted spline and ON-ASCO fitted spline were projected onto the ASCO reference plane for comparison purposes. The ON-ASCO centroid for each eye has been used to horizontally align the data from each eye. The green arrow (Control eye of Rat 1, upper left) schematically depicts the ASCO-ON-ASCO Gap Distance measurement (here showing 1 of a total of 80 radial measurements – see methods). Animal- specific EG vs Control eye overlays of ASCO and ON-ASCO data can be seen in Supplemental Figures 9 and 11, respectively. Global EG eye increases in ASCO radius were present within Animals 2–8. Global EG eye increases in ON-ASCO radius were present within Animals 1 and 3–8. Global EG eye ASCO-ON-ASCO Distance was significantly increased within Animals 2, 4, 5, 6 and 7. The scale is in micrometers. See Supplemental Figure 11 for a similar plot of PSCO and ON-PSCO data.