Table 1. Frequency of sister chromatid exchange in the telomeres of mouse cells (T-SCE).
| Cell type | No. of cells scored | Average no. of Chromosomes per cell | Average no. of T-SCEs per chromosome | Ratio relative to control |
|---|---|---|---|---|
| WT | 82 | 39.3 | 0.0136 | 1.00 |
| scid | 154 | 39.3 | 0.0161 | 1.18 |
| p53−/− | 102 | 39.3 | 0.00698 | 0.513 |
| p53−/−/scid | 103 | 39.7 | 0.0221 | 1.63 |
| p53−/− (200 μM IC86621) | 30 | 71.8 | 0.00279 | 0.205 |
| Control (MLV)a | 100 | 64.3 | 0.0314 | 1.00 |
| Ku70−/− (MLV) | 100 | 52.3 | 0.0417 | 1.33 |
| Ku86−/− (MLV) | 99 | 71.9 | 0.0353 | 1.12 |
| PARP+/+ | 50 | 38.7 | 0.0227 | 1.00 |
| PARP+/+ (10 mM 3AB) | 50 | 37.4 | 0.0305 | 1.34 |
| PARP−/− | 48 | 43.5 | 0.0187 | 0.824 |