Table 3.

Schedule of visits, procedures and assessments

Visit number (month)	Screening visit	1 (Baseline)	2 (3)	3 (6)	4 (9)	5 (12)	6 (15)	7 (18)	8 (21)	9 (24)	10 (27)	11 (30)	12 (33)	13 (36)	14 (39)	15 (42)	16 (45)	17 (48)	18 (51)	19 (54)	20 (57)	21 (60)
Informed consent	X
Review inclusion/exclusion	X
Initial medical history	X
Interval medical history			X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X
Vital signs: (blood pressure, pulse, temperature, respiratory rate)	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X
Measurement of height	X
Weight, BMI, waist circumference	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X
Physical examination	X	X
Oral glucose tolerance test	X					X				X				X				X				X
HbA1c, electrolytes, hematology, lipid profile	X					X				X				X				X				X
Fasting plasma glucose & insulin	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X
Urine microalbumin/ creatinine ratio		X				X				X				X				X				X
Adipocytokines (TNF-alpha, IL-1, IL-6, leptin, adiponectin, resistin)		X				X				X				X				X				X
Block Food Frequency Questionnaire		X		X				X				X				X				X
NHANES III Physical Activity Questionnaire		X
Modifiable Activities Questionnaire		X				X				X				X				X				X
Socioeconomic Status Questionnaire		X				X				X				X				X				X
Body composition (DEXA)			X					X				X				X				X
Indirect calorimetry		X									X								X
Intravenous glucose tolerance test		X					X				X				X						X
Insulin sensitivity test (euglycemic clamp)				X								X								X
Leptin secretion test			X																			X
Genetic repository blood sample	X