Fig. 5.

The effect of phenylbutyrate on cell cycle distribution of LN-229 glioblastoma cell line. The cell cycle was measured by propidium iodide staining followed by flow cytometry analysis. Results are shown for cells treated with 5 and 15 mmol/L PBA for 24 and 48 h versus untreated controls. a Graphical representation of the cell cycle profiles obtained from flow cytometry measurements. b Bar graph presenting the percentage of cell cycle distribution in LN-229 cells. Significant alterations are expressed relative to controls and marked with asterisks. Statistical significance was *p < 0.05 or **p < 0.001