Table 2. Estimated Sensitivity, Specificity, Positive and Negative Predictive Values, and Positive and Negative Likelihood Ratios of MRI Features in Prediction of Malignancya.
| Sensitivity | Specificity | PPV | NPV | PLR | NLR | |
|---|---|---|---|---|---|---|
| Focal | 0.0 (0.0 - 6.2) | 80.0 (51.4 - 94.7) | 0.0 (0.0 - 69.0) | 14.1 (7.8 - 23.8) | 0 | 1.25 (1.21 - 1.29) |
| linear | 53.4 (41.4 - 65.0) | 86.7 (58.4 - 97.7) | 95.1 (82.2 - 99.2) | 27.7 (16.1 - 42.9) | 4.00 (1.18 - 14.82) | 0.54 (0.41 - 0.70) |
| segmental | 41.1 (29.9 - 53.2) | 93.3 (66.0 - 99.7) | 96.8 (81.5 - 99.8) | 24.6 (14.5 - 38.0) | 6.16 (0.91 - 41.77) | 0.63 (0.52 - 0.77) |
| regional | 5.5 (1.8 - 14.2) | 40.0 (17.5 - 67.1) | 30.8 (10.4 - 61.1) | 8.0 (3.3 - 17.2) | 0.09 (0.03 - 0.26) | 2.36 (1.84 - 3.04) |
| homogeneous | 13.7 (7.1 - 24.2) | 73.3 (44.8 - 91.1) | 71.4 (42.0 - 90.4) | 14.9 (9.0 - 25.5) | 0.51 (0.19 - 1.42) | 1.18 (1.02 - 1.35) |
| heterogeneous | 45.2 (33.7 - 57.2) | 40.0 (33.7 - 57.2) | 78.6 (62.8 - 89.2) | 13.0 (5.4 - 27.0) | 0.75 (0.46 - 1.22) | 1.37 (0.91 - 2.05) |
| clumped | 31.5 (21.4 - 43.6) | 86.7 (58.4 - 97.7) | 92.0 (72.5 - 98.6) | 20.6 (11.9 - 33.0) | 2.36 (0.62 - 8.97) | 0.79 (0.66 - 0.94) |
| clustered ring | 9.6 (4.3 - 19.3) | 100.0 (74.7 - 100.0) | 100.0 (56.1 - 100.0) | 18.5 (11.1 - 29.1) | ---- | 0.90 (0.84 - 0.97) |
| asymmetry | 100.0 (93.8 - 100.0) | 20.0 (5.3 - 48.6) | 85.9 (76.2 - 92.2) | 100.0 (31.0 - 100.0) | 1.25 (0.97 - 1.61) | 0 |
Abbreviations: NLR, negative likelihood ratio; NPV, negative predictive value; PLR, positive likelihood ratio; PPV, positive predictive value.
aData are presented as percent(95% Confidence Interval).