TABLE 2.
Central 95% reference intervals for serum concentrations of total 25(OH)D and metabolites stratified by race-ethnicity for persons aged ≥1 y: NHANES 2007–20101
| Total,2nmol/L |
Hispanic,3nmol/L |
Non-Hispanic black, nmol/L |
Non-Hispanic white, nmol/L |
|||||
| Analyte | 2.5th | 97.5th | 2.5th | 97.5th | 2.5th | 97.5th | 2.5th | 97.5th |
| Total 25(OH)D | 23.5 (21.8, 25.1) | 124 (120, 128) | 24.2 (21.8, 25.6) | 95.1 (93.5, 98.0) | 15.4 (13.5, 17.0) | 94.6 (90.1, 99.8) | 30.6 (28.7, 32.3) | 130 (126, 135) |
| 25(OH)D3 | 20.7 (19.4, 22.1) | 120 (117, 124) | 22.3 (19.8, 24.0) | 92.9 (91.3, 96.2) | 13.6 (11.5, 14.9) | 89.6 (86.3, 94.2) | 26.2 (24.8, 27.6) | 126 (123, 131) |
| 25(OH)D2 | <LOD | 21.0 (19.0, 24.2) | <LOD | 9.15 (7.55, 12.4) | <LOD | 20.4 (16.7, 22.9) | <LOD | 22.6 (20.2, 27.6) |
| C3-epi-25(OH)D3 | <LOD | 10.7 (10.2, 11.7) | <LOD | 7.36 (6.91, 7.98) | <LOD | 6.45 (5.59, 7.83) | <LOD | 11.9 (10.8, 13.1) |
Values are percentiles (95% CIs); for sample sizes, see Supplemental Tables 3–6. LOD [2.05 nmol/L for 25(OH)D2 and 1.64 nmol/L for C3-epi-25(OH)D3]; total 25(OH)D, total 25-hydroxyvitamin D [sum of 25(OH)D3 and 25(OH)D2]. C3-epi-25(OH)D3, C3-epimer of 25-hydroxycholecalciferol; LOD, limit of detection; 25(OH)D2, 25-hydroxyergocalciferol; 25(OH)D3, 25-hydroxycholecalciferol.
Estimates for “other” race-ethnicity group (persons with multiethnic background) are not shown but are included in total estimates.
The Hispanic subgroup represents the sum of Mexican-American and other Hispanic ethnicities.