Table 3.

Heritability of change in platelet aggregation between interventions.

Agonist	Clopidogrel Response		DAPT Response		Aspirin Response
	h2 ± SE	p-value	h2 ± SE	p-value	h2 ± SE	p-value
ADP
2 μM	0.23 ± 0.07	3.6×10−4	0.26 ± 0.08	1.5×10−4	0.08 ± 0.09	0.251
5 μM	0.16 ± 0.08	0.019	0.25 ± 0.10	0.003	0.06 ± 0.08	0.249
10 μM	0.24 ± 0.09	9.7×10−8	0.17 ± 0.09	0.023	0.21 ± 0.09	0.006
20 μM	0.33 ± 0.09	1.7×10−5	0.22 ± 0.09	0.006	0.25 ± 0.09	0.001
Collagen
1 μg/mL	0.12 ± 0.08	0.078	0.04 ± 0.13	0.500	0.48 ± 0.10	6.0×10−7
2 μg/mL	0.24 ± 0.09	0.003	0.11 ± 0.09	0.134	0.37 ± 0.09	2.5×10−5
5 μg/mL	0.19 ± 0.08	0.009	0.38 ± 0.09	7.0×10−7	0.24 ± 0.08	4.6×10−4
10 μg/mL	0.14 ± 0.08	0.050	0.57 ± 0.09	5.0×10−13	0.32 ± 0.07	1.0×10−7
Epinephrine	0.10 ± 0.10	0.220	0.21 ± 0.10	0.015	0.52 ± 0.09	5.9×10−10
Arachidonic Acid	0.35 ± 0.08	1.7×10−6	0	0.5	0.37 ± 0.08	1.0×10−7

^*Clopid. = Clopidogrel; h² = heritability; SE = Standard Error; Heritability estimates are adjusted for age and sex.