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. 2016 Feb 4;17(3):171–178. doi: 10.1038/gene.2016.2

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Copyright © 2016 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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RBC CR1 level is negatively associated with α⁺thalassaemia genotype. RBC CR1 level was examined in a total of 3535 children with known α⁺thalassaemia genotypes. Differences in RBC CR1 level by α⁺thalassaemia genotype were compared by multivariate linear regression analysis with adjustment for age, HbS, Sl and McC genotypes. The normal globin genotype (αα/αα) was used as the reference genotype. Error bars represent 95% confidence intervals of the mean RBC CR1 level. Numbers in parenthesis reflect total number of samples tested for each genotype group. Statistically significant differences in RBC CR1 level from the reference genotype are asterisked, ***P<0.001.