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. Author manuscript; available in PMC: 2016 Apr 23.
Published in final edited form as: J Vasc Res. 2016 Mar 31;52(5):347–359. doi: 10.1159/000444526

Figure 7. R-Ras inhibits directional EC migration toward VEGF.

Figure 7

(A and B) R-Ras38V-transduced and control ECs were starved for growth factors for 8 hours and placed into the upper compartment of Transwell® chamber. VEGF (5ng/ml) was added into the lower compartment and incubated for 2 hours. Migration of ECs toward VEGF was quantified. n=5, *p<0.001 (B) R-Ras-silenced ECs were starved for growth factors for 8 hours. Cells were treated with 10 nM SB203580 for 2 hours before migration assay. n=5. *p < 0.05, ns: non-significant difference.