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. Author manuscript; available in PMC: 2016 Apr 23.
Published in final edited form as: Curr Hypertens Rev. 2014;10(4):223–238. doi: 10.2174/157340211004150319123313

Table 1.

The sodium transporters in nephron segments.

Segments Apical Membrane Basolateral Membrane
Proximal tubule NHE 3/2 Na+/K+-ATPase
Sodium/glucose co-transporter 1/2 NHE 1/4
Sodium/phosphate co-transporter 1/2a/2c Sodium/iodide co-transporter
Sodium/sulfate co-transporter 1 Sodium/bicarbonate co-transporter 1
Sodium/monocarboxylate co-transporter 1/2
Sodium/multivitamine co-transporter
Loop of Henle Na+/K+-ATPase
 Descending limb NHE 3
 Thin ascending limb Na+/K+/2Cl− cotransporter 2 NHE 1/4
 Thick ascending limb NHE 3/2
Distal convoluted tubule Na+/Cl− cotransporter Na+/K+-ATPase
NHE 1/4
Collecting duct system Epithelial Na+ channel Na+/K+-ATPase
NHE 1/4

NHE, Sodium-hydrogen exchanger.