Table 2.
Results of bioinformatics analyses on upregulated pathways in HUVECs after TGFβ1 (10 ng/mL) stimulation.
| Pathway analysis | Upregulated gene count | P value |
|---|---|---|
| Hippo signaling pathway | 153 | 0.0002709 |
| Wnt signaling pathway | 139 | 0.0006834 |
| Basal cell carcinoma | 55 | 0.0017771 |
| Hedgehog signaling pathway | 51 | 0.0027492 |
| Pathways in cancer | 327 | 0.0052783 |
| Osteoclast differentiation | 131 | 0.0067513 |
| Melanogenesis | 101 | 0.0073718 |
| Axon guidance | 127 | 0.0095634 |
| Pertussis | 75 | 0.0114669 |
| Neuroactive ligand-receptor interaction | 321 | 0.0157052 |
| Synaptic vesicle cycle | 63 | 0.0158835 |
| NOD-like receptor signaling pathway | 57 | 0.0186762 |
| Acute myeloid leukemia | 57 | 0.0186762 |
| Neurotrophin signaling pathway | 120 | 0.0205091 |
| Focal adhesion | 206 | 0.0236221 |
| Proteoglycans in cancer | 225 | 0.0259569 |
| Adrenergic signaling in cardiomyocytes | 149 | 0.0279908 |
| Notch signaling pathway | 48 | 0.0376197 |
| Prolactin signaling pathway | 72 | 0.0414023 |
| Jak-STAT signaling pathway | 156 | 0.0438904 |
| Cytokine-cytokine receptor interaction | 271 | 0.0439402 |
| Prostate cancer | 89 | 0.0448626 |