Table 2.
Clinical features of the patients with syphilitic uveitis.
| Case | Duration (month) | Ocular findings | FA findings | Other auxiliary examinations | Initial BCVA | BCVA at final visit |
|---|---|---|---|---|---|---|
| 1 | OS: 1 | OS: AC cells 1+; flare 1+; vitreous cells 1+; placoid, yellowish, outer retinal lesions | OS: early irregular hyperfluorescence; progressive hyperfluorescence; late staining | OCT: partial ill-defined IS/OS junction; irregular RPE; a fine epiretinal membrane | OS: 20/200 | OS: 20/25 |
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| 2 | OD: 6 | OD: flare 1+; cataract; vitreous cells 1+; retinal edema and exudates | OD: perivascular leakage; hyperfluorescence; late staining | OCT: ill-defined IS/OS junction; increased central foveal thickening | OD: 20/200 | OD: 20/30 |
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| 3 | OU: 8 | OD: AC cells 2+; flare 2+; cataract; posterior synechiae; Busacca nodules; vitreous cells 3+; fundus blurred; OS: AC cells 1+; flare 2+; cataract; posterior synechiae; Busacca nodules; vitreous cells 3+; fundus blurred | ND | B-scan: diffuse, high reflectivity in vitreous body; retinal edema | OD: HM OS: CF |
OD: 20/50 OS: 20/40 |
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| 4 | OD: 5 OS: 6 |
OU: AC cells 1+; flare 1+; vitreous cells 2+; disk edema; peripheral infiltrates | OU: optic disk leakage; perivascular staining | OCT: OU: optic disk edema; increased thickening of retina | OD: 20/100 OS:20/125 |
OD: 20/20 OS: 20/25 |
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| 5 | OD: 5 OS: 3 |
OD: AC cells 1+; flare 1+; vitreous cells 1+; retinal edema and yellow macular exudative lesion; OS: AC cells 1+; flare 1+; vitreous cells 1+; retinal edema |
OD: early irregular hyperfluorescence; late diffuse staining of the lesion OS: optic disk leakage and perivascular staining |
OCT: OD: irregular retinal contour; ill-defined IS/OS junction; absent external limiting membrane; OS: optic disk edema; retina edema | OD: 20/200 OS: 20/100 |
OD: 20/25 OS: 20/20 |
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| 6 | OD: 1 | OD: AC cells 1+; flare 1+; vitreous cells 2+; diffuse retinal edema; serous retinal detachment | OD: multifocal areas of leakage; late staining | B-scan: medium reflectivity in vitreous body; retinal detachment | OD: CF | OD: 20/32 |
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| 7 | OD: 2 OS: 15 |
OD: AC cells 1+; flare 1+; vitreous cells 1+; yellow-white macular lesion and proliferative membrane OS: AC cells 1+; flare 1+; vitreous cells 1+; retinal edema; exudation; yellow-white lesions at the level of RPE |
OU: early hypofluorescence; late staining | OD: subretinal fluid; fine membrane on the retinal surface OS: subretinal fluid |
OD: 20/200 OS: 20/200 |
OD: 20/40 OS: 20/50 |
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| 8 | OD: 1 OS: 2 |
OU: AC cells 1+; flare 2+; vitreous cells 3+, with yellow-white spots; fundus blurred | ND | B-scan ultrasonography: diffuse, medium to high reflectivity in vitreous body; retinal edema | OU: HM | OD: 20/25 OS: 20/32 |
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| 9 | OD: 6 | OD: AC cells 1+; flare 1+; vitreous cells 1+; retinal splinter hemorrhage; subretinal exudation | OD: early irregular hyperfluorescence; late staining | ND | OD: 20/80 | OD: 20/25 |
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| 10 | OD: 7 OS: 10 |
OD: vitreous cells 1+; retinal edema; ERM; pigmented spots OS: vitreous cells 1+; retinal edema |
OU: retinal vascular leakage; late staining; CME | OCT: OD: increased thickening of neurosensory retina; ERM; CME OS: increased thickening of neurosensory retina; CME |
OD: 20/80 OS: 20/125 |
OD: 20/32 OS: 20/50 |
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| 11 | OU: 2 | OU: AC cells 1+; flare 1+; vitreous cells 1+; hyperemic optic disk and edema; diffuse retinal edema | OU: optic disk leakage; retinal vascular leakage; late staining | OCT: OU: increased thickening of neurosensory retina; subretinal fluid and irregular RPE | OD: 20/100 OS: 20/200 |
OD: 20/20 OS: 20/20 |
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| 12 | OD: 3 OS: 7 |
OD: AC cells 1+; flare 1+; vitreous cells 2+ with yellow spots; retinal edema; yellow macular lesion OS: AC cells 1+; flare 1+; cataract; posterior synechiae; Busacca nodules; vitreous cells 2+ with yellow spots; retinal edema; CME; ERM |
OD: retinal vascular leakage; macular leakage under neurosensory elevation OS: retinal vascular leakage; disc staining; CME; ERM |
VEP: amplitude of P100 marked reduction | OD: 20/125 OS: 20/400 |
OD: 20/32 OS: 20/50 |
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| 13 | OD: 18 OS: 17 |
OU: cataract; pallor optic disk; retinal vascular sheathing | OU: optic disk staining; perivascular leakage; late staining | Flash and pattern ERG and VEP reduced OU | OD: 20/400 OS: 20/250 |
OD: 20/40 OS: 20/25 |
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| 14 | OD: 5 OS: 3 |
OD: cataract; posterior synechiae vitreous cells 1+; midperipheral yellow lesion; CME OS: AC cells 1+; flare 1+; vitreous cells 1+; optic disk edema; retinal edema |
OD: early hypofluorescence; late staining; CME OS: optic disk and retinal vascular leakage; late staining |
ND | OD: 20/125 OS: 20/100 |
OD: 20/40 OS: 20/25 |
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| 15 | OU: 2 | OD: AC cells 2+; flare 1+; cataract; posterior synechiae; vitreous cells 3+ with yellow spots; fundus blurred OS: AC cells 1+; flare 1+; vitreous cells 3+ with yellow spots; fundus blurred |
ND | B-scan ultrasonography: high reflectivity in vitreous cavity with retinal edema | OD: CF OS: 20/500 |
OD: 20/60 OS: 20/50 |
AC: anterior chamber; BCVA: best corrected visual acuity; CF: counting fingers; CME: cystoid macular edema; ERG: electroretinogram; ERM: epiretinal membrane; FA: fluorescein angiography; HM: hand movement; IS/OS: inner segment/outer segment; ND: not done; OCT: optical coherence tomography; OD: right eye; OS: left eye; OU: both eyes; VEP: visual evoked potential.