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Id2 network model in insulin signaling, thermogenesis, and adipogenesis pathways. A schematized and partial view of the signaling pathway indicating its major downstream targets and factors susceptible to interfering with signaling. Function of ID2 is not necessarily limited to the nucleus [8]. ↑ or ↓, up- or downregulation of gene expression, respectively, as determined by PCR array analysis in the current study.
