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Effects of peripheral (i.pl) or central (i.c.v) administration of 2-BFI on formalin-induced flinching (n=6 per group). Vertical axis, total flinches during 0–10 min (phase 1, top) and 20–60 min (phase 2, bottom) following formalin treatment; horixontal axis, drug dose (mg/kg or µg). * P < 0.05 as compared to vehicle control.
