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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: J Clin Immunol. 2016 Apr 11;36(4):341–353. doi: 10.1007/s10875-016-0266-5

Fig. 4. The TRB repertoire of LIG4-deficient patients P1-P2 shows minimal skewing.

Fig. 4

The global usage of unique TRB sequences is demonstrated for 3 healthy controls and P1-P3 on a heat map showing TCRBV genes joint with TCRBJ genes. The frequency of gene usage is color-coded, using yellow and red to indicate rare and most common pairing of V-J genes, respectively. Blank boxes indicate absence of that specific rearrangement in the total population of sequences obtained.