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. Author manuscript; available in PMC: 2017 Apr 21.
Published in final edited form as: Cell. 2016 Apr 13;165(3):656–667. doi: 10.1016/j.cell.2016.03.021

Figure 2. Viral dissemination to distal tissues.

Figure 2

(A) Mean log RNA copies / 108 cell equivalents and probability of each tissue positive for virus is plotted versus the day of necropsy. Decline in levels of viral RNA in female reproductive tract tissues from day 1 to day 7 likely reflects clearance of residual inoculum challenge virus, with the subsequent increase from day 7 to day 10 likely reflecting productive infection. (B) Statistical comparisons of the tissue viral loads and the percent of each tissue positive for virus in animals necropsied on days 1, 3, 7, and 10 following SIVmac251 inoculation as compared with uninoculated controls (Naïve) by linear mixed models and Fisher’s exact tests.