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. Author manuscript; available in PMC: 2017 Apr 21.
Published in final edited form as: Cell. 2016 Apr 13;165(3):656–667. doi: 10.1016/j.cell.2016.03.021

Figure 5. NLRX1 expression is correlated inversely with antiviral gene expression and is correlated directly with viral RNA.

Figure 5

(A) Early NLRX1 expression is inversely correlated with antiviral restriction factors in FRT. F-test heatmap depicts viral RNA positive FRT tissues for NLRX1 or with an antiviral gene filter (20 samples from 8 monkeys). (B) Linear regression analysis of viral RNA levels and gene expression in viral RNA positive gastrointestinal tissues. Heatmap represents the top positively correlated proinflammatory genes, including NLRX1, which were part of the full regression signature. (C) Correlation analysis between NLRX1 expression and viral RNA levels in viral RNA positive gastrointestinal tissues. (D) Bee-swarm plot shows that samples with the highest NLRX1 expression had the highest viral RNA levels. P-values reflect Wilcoxon rank sum tests. See also Supplementary Figures S4 and S6.