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MMP-2 (left / blue crosshatched columns) and MMP-9 (right / red columns) activities in SC depending on metastatic index. N0М0 – no metastasis; N1-2M0 - regional lymph nodes metastasis; N0-2M1 – distant metastasis. The reliable negative correlation (p < 0.05) between the MMP-2 activity and M stage is obtained
