Table 3.
The effect of aquatic extract of stevia on biochemical parameters in different experimental groups
| Experimental groups | Control (A) | Diabetic (B) | Pioglitazone (C) | Stevia (D) |
|---|---|---|---|---|
| Body weight (gr) | 290.0±6.3 a** b** | 174.2±8.3 | 209.1±13.2 a* b* | 185.0±6.9 |
| Serum FBS (mg/dl) | 95.1±2.9 a** b* | 610.5±22.2 b** | 494.1±31.1a* b** | 210.0±24.2 a** |
| Serum TG (mg/dl) | 58.5±5.3 a** | 244.62±23.3 b** | 178.3±26.5 a* b** | 46.9±7.0 a** |
| Serum cholestrol (mg/dl) | 56.7±4.1 | 52.3±4.1 | 53.6±2.8 | 63.7±5.0 |
| Serum HDL (mg/dl) | 24.2±1.3 b* | 21.0±2.3 b* | 28.0±1.4 a* | 29.0±2.1 a* |
| Serum LDL (mg/dl) | 14.8±1.4 | 18.8±3.3 | 15.1±1.8 | 14.4±2.9 |
| ALT (IU/ml) | 50.2±4.5 a** b* | 427.1±105.4 b* | 242.8±37.6 a* | 248.6±28.6 a* |
| AST (IU/ml) | 149.7±6.9 a** b* | 536.5±55.7 b** | 328.6±39.4 a** | 302±25.2 a** |
| MDA (nmol/mg protein) | 0.40±0.04 a** | 1.4±0.08 b** | 0.85±0.04 a** b** | 0.45±0.04 a** |
| Catalase activity (IU/mg protein) | 29.4±2.8 a** | 9.9±2.2 b** | 24.7±2.4 a** b* | 33.7±2.0 a** |
Results are presented as mean±SEM, n=12.
a)
Compared with diabetic groups.
b)
Compared with stevia groups.
*
p<0.05,
**
p<0.01