Table 7.
Pharmacokinetic parameters of clonidine hydrochloride after single oral dose of the test and reference product (Mean±SD)
| Pharmacokinetics parameters | Test | Reference |
|---|---|---|
| Cmax (ng/ml) | 6.16± 0.32 | 6.21±0.07 |
| t max (hr) | 30.12±0.86 | 30.13±0.73 |
| AUC 0-t (ng/L hr) | 290.37±1.13 | 293.39±1.22 |
| AUC 0-∞ (ng/L hr) | 350.17±1.98 | 352.96±1.67 |
| T 1/2 (hr) | 120.12±1.90 | 120.96±1.54 |
| Cl/F (L/hr) | 22.1±1.01 | 23.6±0.56 |