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. 2016 Apr 23;17:304. doi: 10.1186/s12864-016-2623-4

Table 1.

Antioxidant-associated genes upregulated by cAMP in astrocytes (fold-change)

Catalase Cat (2.2)
Superoxidase dismutases Sod2 (1.4), Sod3 (5.3)
Peroxiredoxins and sulfiredoxins Prdx1 (1.8), Prdx2 (1.5), Prdx5 (1.5), Srxn1 (4.1)
Cystine/glutamate transporter Slc7a11 (9.6)
Glutamate-cysteine ligases Gclc (5.3), Gclm (3.1)
Gluthatione synthetase and transferases Gss (1.5), Gsta1 (15.7), Gsta2 (6.9), Gsta3 (6.6), Gsta4 (2.3), Gstm5 (1.6), Mgst1 (4.4), Mgst2 (7.7)
Glutathione peroxidases and reductases Gpx4 (1.6), Gsr (1.5)
NADPH-quinone oxidoreductase and heme oxygenase Nqo1 (4.4)
Thioredoxins and thioredoxin reductases Txn2 (1.6), Txnrd1 (3.3)
Metallothioneins and selenoproteins Mt1 (1.6), Mt2 (1.5), Sepp1 (1.3)
Ascorbate and glucose/dehydroascorbate transporters Slc23a2 (4.5), Slc2a1 (3.9), Slc2a4 (1.4), Slc2a8 (1.7), Slc2a13 (2.2)
α-tocopherol transfer protein Ttpa (2.2)