Table 2.

Selected categories and genes down-regulated by cAMP elevation in astrocytes

General category
GO category	NES	FDR q-value	Gene	ID	Protein name	FC
Cell cycle and apoptosis
Mitosis	−1,71	0.018	Ccna2	12428	cyclin A2	- 4,2
DNA directed DNA polymerase activity	−1,76	0.012	Pold1	18971	polymerase (DNA directed), delta 1, catalytic subunit	−2,3
Cytokinesis	−1,69	0.02	Myh10	77579	myosin, heavy polypeptide 10, non-muscle	−3,7
Cell signalling
Ras protein signal transduction	−1,77	0.012	Igf1	16000	insulin-like growth factor 1	−6.1
Neuropeptide hormone activity	−1,29	0.183	Npy	109648	neuropeptide Y	- 3,5
Cytoskeleton, cell shape and motility
Collagen	−1,75	0.013	Col5a2	12832	collagen type V a2	- 6,7
Structural constituent of cytoskeleton	−1,67	0.023	Tpm1	22003	tropomyosin 1, alpha	−3.1
Cell development
Cell development	−1,85	0.008	Igfbp3	16009	insulin-like growth factor binding protein 3	- 4,1
Cellular metabolism
Proteoglycan metabolic process	−1,76	0.012	Chst7	60322	chondroitin 6-sulfotransferase 7	- 2,9
Immune response
Inflammatory response	−1,82	0.01	Ccl2	20296	chemokine (C-C motif) ligand 2	- 2,1
			Cxcl10	15945	chemokine (C-X-C motif) ligand 10	−3,7
Others
Lipid raft	−2,01	0.0088	Cav1	12389	caveolin 1	- 4,0