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. Author manuscript; available in PMC: 2017 Feb 24.
Published in final edited form as: Audiol Neurootol. 2016 Feb 24;21(2):72–79. doi: 10.1159/000442514

Figure 1.

Figure 1

Summary of injection, leaks and sealing procedures. A: Section of the basal turn of scala tympani from a guinea pig with fluid compartments labeled. Abbreviations are RW: round window; ST: scala tympani; SM: scala media; CA: cochlear aqueduct. B: Schematic showing injection through the RW membrane. The size of the injection pipette has been grossly exaggerated for clarity. C: Injected solution is displaced through the RW membrane perforation made by the injection pipette, driven by CSF entering through the cochlear aqueduct (green arrows). D: Internal sealing may be provided if the marker is injected as a viscous gel, which plugs the perforation site preventing fluid efflux. E: External sealing is achieved by applying adhesive (green) to the exterior surface of the RW membrane.