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. Author manuscript; available in PMC: 2016 Apr 24.
Published in final edited form as: Cell. 2015 Apr 16;161(3):622–633. doi: 10.1016/j.cell.2015.03.022

Figure 4. Remote Control of Breathing.

Figure 4

(A) Respiratory effects following focal vagus nerve illumination (yellow shading) in lox-ChR2, Vglut2-ChR2, P2ry1-ChR2, Npy2r-ChR2, and Gpr65-ChR2 mice. Respiratory rhythms (representative traces) were measured using a pressure transducer via trachea cannula. Changes in respiration rate and minute volume were calculated over time, with each data point reflecting a 5 s bin.

(B) Light-induced changes in respiration rate, tidal volume, and minute volume were calculated over the 10 s trial (n = 4–8 as indicated, mean ± SEM, and ***p < 0.001). See also Figures S5 and S6.